diff --git a/scripts/generate_rust_target.rs b/scripts/generate_rust_target.rs
index 836fdf622c2dea..86372077731344 100644
--- a/scripts/generate_rust_target.rs
+++ b/scripts/generate_rust_target.rs
@@ -173,6 +173,14 @@ fn main() {
             features += ",+retpoline-indirect-branches";
             features += ",+retpoline-indirect-calls";
         }
+        if cfg.has("MITIGATION_SLS") {
+            // The kernel uses `-mharden-sls=all`, which Clang maps to both these target features in
+            // `clang/lib/Driver/ToolChains/Arch/X86.cpp`. These should be eventually enabled via
+            // `-Ctarget-feature` when `rustc` starts recognizing them (or via a new dedicated
+            // flag); see https://github.com/rust-lang/rust/issues/116851.
+            features += ",+harden-sls-ijmp";
+            features += ",+harden-sls-ret";
+        }
         ts.push("features", features);
         ts.push("llvm-target", "x86_64-linux-gnu");
         ts.push("target-pointer-width", "64");