diff --git a/packages/components/src/button/README.md b/packages/components/src/button/README.md
index a8cdcf82c96657..e8b0e7ea697083 100644
--- a/packages/components/src/button/README.md
+++ b/packages/components/src/button/README.md
@@ -115,6 +115,17 @@ The presence of a `href` prop determines whether an `anchor` element is rendered
 
 Props not included in this set will be applied to the `a` or `button` element.
 
+#### `accessibleWhenDisabled`: `boolean`
+
+Whether to keep the button focusable when disabled.
+
+In most cases, it is recommended to set this to `true`. Disabling a control without maintaining focusability can cause accessibility issues, by hiding their presence from screen reader users, or by preventing focus from returning to a trigger element.
+
+Learn more about the [focusability of disabled controls](https://www.w3.org/WAI/ARIA/apg/practices/keyboard-interface/#focusabilityofdisabledcontrols) in the WAI-ARIA Authoring Practices Guide.
+
+-   Required: No
+-   Default: `false`
+
 #### `children`: `ReactNode`
 
 The button's children.
@@ -137,6 +148,8 @@ An accessible description for the button.
 
 Whether the button is disabled. If `true`, this will force a `button` element to be rendered, even when an `href` is given.
 
+In most cases, it is recommended to also set the `accessibleWhenDisabled` prop to `true`.
+
 -   Required: No
 
 #### `href`: `string`
diff --git a/packages/components/src/button/index.tsx b/packages/components/src/button/index.tsx
index e2ef34f35712e7..ac495007838403 100644
--- a/packages/components/src/button/index.tsx
+++ b/packages/components/src/button/index.tsx
@@ -29,6 +29,7 @@ import { positionToPlacement } from '../popover/utils';
 const disabledEventsOnDisabledButton = [ 'onMouseDown', 'onClick' ] as const;
 
 function useDeprecatedProps( {
+	__experimentalIsFocusable,
 	isDefault,
 	isPrimary,
 	isSecondary,
@@ -43,7 +44,8 @@ function useDeprecatedProps( {
 	let computedSize = size;
 	let computedVariant = variant;
 
-	const newProps: { 'aria-pressed'?: boolean } = {
+	const newProps = {
+		accessibleWhenDisabled: __experimentalIsFocusable,
 		// @todo Mark `isPressed` as deprecated
 		'aria-pressed': isPressed,
 	};
@@ -91,6 +93,7 @@ export function UnforwardedButton(
 ) {
 	const {
 		__next40pxDefaultSize,
+		accessibleWhenDisabled,
 		isBusy,
 		isDestructive,
 		className,
@@ -106,7 +109,6 @@ export function UnforwardedButton(
 		size = 'default',
 		text,
 		variant,
-		__experimentalIsFocusable: isFocusable,
 		describedBy,
 		...buttonOrAnchorProps
 	} = useDeprecatedProps( props );
@@ -159,7 +161,7 @@ export function UnforwardedButton(
 		'has-icon': !! icon,
 	} );
 
-	const trulyDisabled = disabled && ! isFocusable;
+	const trulyDisabled = disabled && ! accessibleWhenDisabled;
 	const Tag = href !== undefined && ! trulyDisabled ? 'a' : 'button';
 	const buttonProps: ComponentPropsWithoutRef< 'button' > =
 		Tag === 'button'
@@ -177,7 +179,7 @@ export function UnforwardedButton(
 	const disableEventProps: {
 		[ key: string ]: ( event: MouseEvent ) => void;
 	} = {};
-	if ( disabled && isFocusable ) {
+	if ( disabled && accessibleWhenDisabled ) {
 		// In this case, the button will be disabled, but still focusable and
 		// perceivable by screen reader users.
 		buttonProps[ 'aria-disabled' ] = true;
diff --git a/packages/components/src/button/test/index.tsx b/packages/components/src/button/test/index.tsx
index 9d8980e04c9313..d13ed65eac26a3 100644
--- a/packages/components/src/button/test/index.tsx
+++ b/packages/components/src/button/test/index.tsx
@@ -241,7 +241,7 @@ describe( 'Button', () => {
 		} );
 
 		it( 'should add only aria-disabled attribute when disabled and isFocusable are true', () => {
-			render( <Button disabled __experimentalIsFocusable /> );
+			render( <Button disabled accessibleWhenDisabled /> );
 			const button = screen.getByRole( 'button' );
 
 			expect( button ).toBeEnabled();
@@ -617,6 +617,14 @@ describe( 'Button', () => {
 				'mixed'
 			);
 		} );
+
+		it( 'should not break when the legacy __experimentalIsFocusable prop is passed', () => {
+			render( <Button disabled __experimentalIsFocusable /> );
+			const button = screen.getByRole( 'button' );
+
+			expect( button ).toBeEnabled();
+			expect( button ).toHaveAttribute( 'aria-disabled' );
+		} );
 	} );
 
 	describe( 'static typing', () => {
@@ -632,7 +640,7 @@ describe( 'Button', () => {
 			{ /* @ts-expect-error */ }
 			<Button type="invalidtype" />
 			{ /* @ts-expect-error - although the runtime behavior will allow this to be an anchor, this is probably a mistake. */ }
-			<Button disabled __experimentalIsFocusable href="foo" />
+			<Button disabled accessibleWhenDisabled href="foo" />
 		</>;
 	} );
 } );
diff --git a/packages/components/src/button/types.ts b/packages/components/src/button/types.ts
index ce6db4b3e914bc..cba06ade2d02ca 100644
--- a/packages/components/src/button/types.ts
+++ b/packages/components/src/button/types.ts
@@ -25,6 +25,19 @@ type BaseButtonProps = {
 	 * @default false
 	 */
 	__next40pxDefaultSize?: boolean;
+	/**
+	 * Whether to keep the button focusable when disabled.
+	 *
+	 * In most cases, it is recommended to set this to `true`. Disabling a control without maintaining focusability
+	 * can cause accessibility issues, by hiding their presence from screen reader users,
+	 * or by preventing focus from returning to a trigger element.
+	 *
+	 * Learn more about the [focusability of disabled controls](https://www.w3.org/WAI/ARIA/apg/practices/keyboard-interface/#focusabilityofdisabledcontrols)
+	 * in the WAI-ARIA Authoring Practices Guide.
+	 *
+	 * @default false
+	 */
+	accessibleWhenDisabled?: boolean;
 	/**
 	 * The button's children.
 	 */
@@ -105,28 +118,24 @@ type BaseButtonProps = {
 	 * 'link' (the link button styles)
 	 */
 	variant?: 'primary' | 'secondary' | 'tertiary' | 'link';
-	/**
-	 * Whether to keep the button focusable when disabled.
-	 *
-	 * @default false
-	 */
-	__experimentalIsFocusable?: boolean;
 };
 
 type _ButtonProps = {
 	/**
-	 * Whether the button is disabled.
+	 * Whether the button is disabled. If `true`, this will force a `button` element
+	 * to be rendered, even when an `href` is given.
 	 *
-	 * If `true`, this will force a `button` element to be rendered, even when an `href` is given.
+	 * In most cases, it is recommended to also set the `accessibleWhenDisabled` prop to `true`.
 	 */
 	disabled?: boolean;
 };
 
 type AnchorProps = {
 	/**
-	 * Whether the button is disabled.
+	 * Whether the button is disabled. If `true`, this will force a `button` element
+	 * to be rendered, even when an `href` is given.
 	 *
-	 * If `true`, this will force a `button` element to be rendered, even when an `href` is given.
+	 * In most cases, it is recommended to also set the `accessibleWhenDisabled` prop to `true`.
 	 */
 	disabled?: false;
 	/**
@@ -140,6 +149,14 @@ type AnchorProps = {
 };
 
 export type DeprecatedButtonProps = {
+	/**
+	 * Whether to keep the button focusable when disabled.
+	 *
+	 * @default false
+	 * @deprecated Use the `accessibleWhenDisabled` prop instead.
+	 * @ignore
+	 */
+	__experimentalIsFocusable?: boolean;
 	/**
 	 * Gives the button a default style.
 	 *