diff --git a/agent/stats/utils_unix.go b/agent/stats/utils_unix.go
index b68c7a1889d..b4f384c90a3 100644
--- a/agent/stats/utils_unix.go
+++ b/agent/stats/utils_unix.go
@@ -27,7 +27,7 @@ import (
 // dockerStatsToContainerStats returns a new object of the ContainerStats object from docker stats.
 func dockerStatsToContainerStats(dockerStats *types.StatsJSON) (*ContainerStats, error) {
 	cpuUsage := dockerStats.CPUStats.CPUUsage.TotalUsage / numCores
-	memoryUsage := dockerStats.MemoryStats.Usage - dockerStats.MemoryStats.Stats["cache"]
+	memoryUsage := getMemUsage(dockerStats.MemoryStats)
 	storageReadBytes, storageWriteBytes := getStorageStats(dockerStats)
 	networkStats := getNetworkStats(dockerStats)
 	return &ContainerStats{
@@ -40,6 +40,21 @@ func dockerStatsToContainerStats(dockerStats *types.StatsJSON) (*ContainerStats,
 	}, nil
 }
 
+func getMemUsage(mem types.MemoryStats) uint64 {
+	if config.CgroupV2 {
+		// for cgroupv2 systems, mem usage calculation uses the same method that the docker cli uses
+		// https://github.com/docker/cli/blob/e198123693b1aaa724041fff602c7d75c8fe4b57/cli/command/container/stats_helpers.go#L227-L249
+		// see https://github.com/aws/amazon-ecs-agent/issues/3323
+		if v, ok := mem.Stats["inactive_file"]; ok && v < mem.Usage {
+			return mem.Usage - v
+		}
+	}
+	if v, ok := mem.Stats["cache"]; ok && v < mem.Usage {
+		return mem.Usage - v
+	}
+	return mem.Usage
+}
+
 func validateDockerStats(dockerStats *types.StatsJSON) error {
 	if config.CgroupV2 {
 		// PercpuUsage is not available in cgroupv2