diff --git a/.gitignore b/.gitignore
index f30e0b6dd..9fb4e43f0 100644
--- a/.gitignore
+++ b/.gitignore
@@ -134,5 +134,6 @@ scratch/
 docs/_site
 docker/edges.tsv.gz
 docker/nodes.tsv.gz
+docker/embeddings.tsv.gz
 mira/dkg/resources/ncit.obo
 docker/epi.sh
diff --git a/docker/Dockerfile b/docker/Dockerfile
index 667a53f85..7254d906f 100644
--- a/docker/Dockerfile
+++ b/docker/Dockerfile
@@ -16,19 +16,22 @@ RUN apt-get update && \
 
 ARG version=2023-10-19
 ARG domain=climate
+ARG embeddings_path=/sw/embeddings.tsv.gz
 # This latter is used in the code
 ENV MIRA_DOMAIN=${domain}
+ENV EMBEDDINGS_PATH=${embeddings_path}
 
 # Download graph content and ingest into neo4j
 RUN wget -O /sw/nodes.tsv.gz https://askem-mira.s3.amazonaws.com/dkg/$domain/build/$version/nodes.tsv.gz && \
     wget -O /sw/edges.tsv.gz https://askem-mira.s3.amazonaws.com/dkg/$domain/build/$version/edges.tsv.gz && \
+    wget -O $embeddings_path https://askem-mira.s3.amazonaws.com/dkg/$domain/build/$version/embeddings.tsv.gz && \
     sed -i 's/#dbms.default_listen_address/dbms.default_listen_address/' /etc/neo4j/neo4j.conf && \
     sed -i 's/#dbms.security.auth_enabled/dbms.security.auth_enabled/' /etc/neo4j/neo4j.conf && \
     neo4j-admin import --delimiter='TAB' --skip-duplicate-nodes=true --skip-bad-relationships=true --nodes /sw/nodes.tsv.gz --relationships /sw/edges.tsv.gz
 
 # Python packages
 RUN python -m pip install --upgrade pip && \
-    python -m pip install git+https://github.com/indralab/mira.git@main#egg=mira[web,uvicorn,dkg-client] && \
+    python -m pip install git+https://github.com/gyorilab/mira.git@main#egg=mira[web,uvicorn,dkg-client] && \
     python -m pip uninstall -y flask_bootstrap && \
     python -m pip uninstall -y bootstrap_flask && \
     python -m pip install bootstrap_flask && \
@@ -37,7 +40,7 @@ RUN python -m pip install --upgrade pip && \
     python -m pip install --no-dependencies --ignore-requires-python sbmlmath
 
 # Copy the example json for reconstructing the ode semantics
-RUN wget -O /sw/sir_flux_span.json https://raw.githubusercontent.com/indralab/mira/main/tests/sir_flux_span.json
+RUN wget -O /sw/sir_flux_span.json https://raw.githubusercontent.com/gyorilab/mira/main/tests/sir_flux_span.json
 
 COPY startup.sh startup.sh
 ENTRYPOINT ["/bin/bash", "/sw/startup.sh"]
diff --git a/docker/Dockerfile.local b/docker/Dockerfile.local
index abeb5b6ba..c1bf465c1 100644
--- a/docker/Dockerfile.local
+++ b/docker/Dockerfile.local
@@ -13,10 +13,13 @@ RUN apt-get update && \
     ln -s /usr/bin/python3 /usr/bin/python
 
 ARG branch=main
+ARG embeddings_path=/sw/embeddings.tsv.gz
+ENV EMBEDDINGS_PATH=${embeddings_path}
 
 # Add graph content
 COPY nodes.tsv.gz /sw/nodes.tsv.gz
 COPY edges.tsv.gz /sw/edges.tsv.gz
+COPY embeddings.tsv.gz ${embeddings_path}
 
 # Ingest graph content into neo4j
 RUN sed -i 's/#dbms.default_listen_address/dbms.default_listen_address/' /etc/neo4j/neo4j.conf && \
@@ -24,7 +27,7 @@ RUN sed -i 's/#dbms.default_listen_address/dbms.default_listen_address/' /etc/ne
     neo4j-admin import --delimiter='TAB' --skip-duplicate-nodes=true --skip-bad-relationships=true --nodes /sw/nodes.tsv.gz --relationships /sw/edges.tsv.gz
 
 # Python packages
-RUN python -m pip install git+https://github.com/indralab/mira.git@$branch#egg=mira[web,uvicorn,dkg-client] && \
+RUN python -m pip install git+https://github.com/gyorilab/mira.git@$branch#egg=mira[web,uvicorn,dkg-client] && \
     python -m pip uninstall -y flask_bootstrap && \
     python -m pip uninstall -y bootstrap_flask && \
     python -m pip install bootstrap_flask
diff --git a/docker/README.md b/docker/README.md
index d6fc9bfa7..d009ec30d 100644
--- a/docker/README.md
+++ b/docker/README.md
@@ -22,24 +22,23 @@ this folder and use:
 export DOMAIN=epi
 cp ~/.data/mira/$DOMAIN/nodes.tsv.gz nodes.tsv.gz
 cp ~/.data/mira/$DOMAIN/edges.tsv.gz edges.tsv.gz
+cp ~/.data/mira/$DOMAIN/embeddings.tsv.gz embeddings.tsv.gz
 
 # Build docker
-docker build --file Dockerfile.local --tag mira_$DOMAIN_dkg:latest .
+docker build --file Dockerfile.local --tag mira:latest .
 ```
 
 Once the build finished, you can run the container locally as:
 
 ```shell
 # Option 1: run in the background
-docker run --detach -p 8771:8771 -e MIRA_NEO4J_URL=bolt://0.0.0.0:7687 --name mira_$DOMAIN_dkg mira_$DOMAIN_dkg:latest
+docker run --detach -p 8771:8771 -p 7687:7687 -e MIRA_NEO4J_URL=bolt://0.0.0.0:7687 --name mira mira:latest
 
 # Option 2: run ephemerally
-docker run -p 8771:8771 -e MIRA_NEO4J_URL=bolt://0.0.0.0:7687 mira_$DOMAIN_dkg:latest
+docker run -p 8771:8771 -p 7687:7687 -e MIRA_NEO4J_URL=bolt://0.0.0.0:7687 mira:latest
 ```
 
-This exposes a REST API at `http://localhost:8771`. Note that the `--detach` flag
-runs the container in the background. If you want to expose Neo4j's bolt port, also
-add `-p 7687:7687`. Note that 
+This exposes a REST API at `http://localhost:8771`. This also exposes Neo4j's bolt port at port 7687.
 
 ## MIRA Metaregistry
 
diff --git a/mira/dkg/api.py b/mira/dkg/api.py
index 9f1975b40..73bfb3e5d 100644
--- a/mira/dkg/api.py
+++ b/mira/dkg/api.py
@@ -1,14 +1,16 @@
 """API endpoints."""
 
+import itertools as itt
 from typing import Any, List, Mapping, Optional, Union
 
 import pydantic
-from fastapi import APIRouter, Body, Path, Query, Request, HTTPException
+from fastapi import APIRouter, Body, HTTPException, Path, Query, Request
 from neo4j.graph import Relationship
 from pydantic import BaseModel, Field
+from scipy.spatial import distance
 from typing_extensions import Literal
 
-from mira.dkg.client import Entity, AskemEntity
+from mira.dkg.client import AskemEntity, Entity
 from mira.dkg.utils import DKG_REFINER_RELS
 
 __all__ = [
@@ -444,3 +446,69 @@ def common_parent(
     entity = request.app.state.client.get_common_parents(query.curie1,
                                                          query.curie2)
     return entity
+
+
+class Distance(BaseModel):
+    """Represents the distance between two entities."""
+
+    source: str = Field(..., title="source CURIE")
+    target: str = Field(..., title="target CURIE")
+    distance: float = Field(..., title="cosine distance")
+
+
+@api_blueprint.post(
+    "/entity_similarity", response_model=List[Distance], tags=["entities"]
+)
+def entity_similarity(
+    request: Request,
+    sources: List[str] = Body(
+        ...,
+        title="source CURIEs",
+        examples=[["ido:0000511", "ido:0000592", "ido:0000597", "ido:0000514"]],
+    ),
+    targets: Optional[List[str]] = Body(
+        default=None,
+        title="target CURIEs",
+        description="If not given, source queries used for all-by-all comparison",
+        examples=[["ido:0000566", "ido:0000567"]],
+    ),
+):
+    """Get the pairwise similarities between elements referenced by CURIEs in the first list and second list."""
+    """Test locally with:
+    
+    import requests
+
+    def main():
+        curies = ["probonto:k0000000", "probonto:k0000007", "probonto:k0000008"]
+        res = requests.post(
+            "http://0.0.0.0:8771/api/entity_similarity",
+            json={"sources": curies, "targets": curies},
+        )
+        res.raise_for_status()
+        print(res.json())
+
+    if __name__ == "__main__":
+        main()    
+    """
+    vectors = request.app.state.vectors
+    if not vectors:
+        raise HTTPException(
+            status_code=500, detail="No entity vectors available"
+        )
+    if targets is None:
+        targets = sources
+    rv = []
+    for source, target in itt.product(sources, targets):
+        if source == target:
+            continue
+        source_vector = vectors.get(source)
+        if source_vector is None:
+            continue
+        target_vector = vectors.get(target)
+        if target_vector is None:
+            continue
+        cosine_distance = distance.cosine(source_vector, target_vector)
+        rv.append(
+            Distance(source=source, target=target, distance=cosine_distance)
+        )
+    return rv
diff --git a/mira/dkg/model.py b/mira/dkg/model.py
index 4c209829c..c1dc6d15a 100644
--- a/mira/dkg/model.py
+++ b/mira/dkg/model.py
@@ -728,14 +728,18 @@ def askepetrinet_model_comparison(
     return resp
 
 
-flux_span_path = docker_test_file_path if docker_test_file_path.exists() else \
-    test_file_path
+if docker_test_file_path.exists():
+    flux_span_query_example = json.loads(docker_test_file_path.read_text())
+elif test_file_path.exists():
+    flux_span_query_example = json.loads(test_file_path.read_text())
+else:
+    flux_span_query_example = None
 
 
 class FluxSpanQuery(BaseModel):
     model: Dict[str, Any] = Field(
         ...,
-        example=json.load(flux_span_path.open()),
+        example=flux_span_query_example,
         description="The model to recover the ODE-semantics from.",
     )
 
diff --git a/mira/dkg/utils.py b/mira/dkg/utils.py
index 56b9c5397..6b62b5023 100644
--- a/mira/dkg/utils.py
+++ b/mira/dkg/utils.py
@@ -1,28 +1,32 @@
 """Utilities and constants for the MIRA app."""
 
 from dataclasses import dataclass
-from typing import List
+from pathlib import Path
+from typing import Dict, List
 
+import numpy as np
 from gilda.grounder import Grounder
 
-from mira.dkg.client import Neo4jClient, Entity
+from mira.dkg.client import Entity, Neo4jClient
 from mira.metamodel import RefinementClosure
 
 __all__ = [
     "MiraState",
     "PREFIXES",
     "DKG_REFINER_RELS",
+    "DOCKER_FILES_ROOT",
 ]
 
 
 @dataclass
 class MiraState:
-    """All of the state associated with the MIRA app."""
+    """Represents the state associated with the MIRA app."""
 
     client: Neo4jClient
     grounder: Grounder
     refinement_closure: RefinementClosure
     lexical_dump: List[Entity]
+    vectors: Dict[str, np.array]
 
 
 #: A list of all prefixes used in MIRA
@@ -69,3 +73,6 @@ class MiraState:
 
 #: A list of all relation types that are considered refinement relations
 DKG_REFINER_RELS = ["subclassof", "part_of"]
+
+#: The root path of the MIRA app when running in a container
+DOCKER_FILES_ROOT = Path("/sw")
diff --git a/mira/dkg/wsgi.py b/mira/dkg/wsgi.py
index 4af73fbe1..179cea73c 100644
--- a/mira/dkg/wsgi.py
+++ b/mira/dkg/wsgi.py
@@ -1,10 +1,14 @@
 """Neo4j client module."""
 
+import csv
+import gzip
 import logging
 import os
+from pathlib import Path
 from textwrap import dedent
 
 import flask
+import numpy as np
 from fastapi import FastAPI
 from fastapi.middleware.wsgi import WSGIMiddleware
 from flask_bootstrap import Bootstrap5
@@ -13,17 +17,19 @@
 from mira.dkg.client import Neo4jClient
 from mira.dkg.grounding import grounding_blueprint
 from mira.dkg.ui import ui_blueprint
-from mira.dkg.utils import PREFIXES, MiraState
+from mira.dkg.utils import PREFIXES, MiraState, DOCKER_FILES_ROOT
 from mira.metamodel import RefinementClosure
 
-logger = logging.getLogger(__name__)
-
-
 __all__ = [
     "flask_app",
     "app",
 ]
 
+logger = logging.getLogger(__name__)
+
+EMBEDDINGS_PATH_DOCKER = Path(
+    os.getenv("EMBEDDINGS_PATH", DOCKER_FILES_ROOT / "embeddings.tsv.gz")
+)
 DOMAIN = os.getenv("MIRA_DOMAIN")
 
 tags_metadata = [
@@ -46,7 +52,7 @@
     {
         "name": "relations",
         "description": "Query relation data",
-    }
+    },
 ]
 
 
@@ -87,6 +93,21 @@ def startup_event():
     logger.info("Running app startup function")
     Bootstrap5(flask_app)
 
+    if not EMBEDDINGS_PATH_DOCKER.is_file():
+        logger.warning(
+            f"Embeddings file {EMBEDDINGS_PATH_DOCKER} not found, skipping "
+            f"loading of embeddings"
+        )
+        vectors = {}
+    else:
+        with gzip.open(EMBEDDINGS_PATH_DOCKER, "rt") as file:
+            reader = csv.reader(file, delimiter="\t")
+            next(reader)  # skip header
+            vectors = {
+                curie: np.array([float(p) for p in parts])
+                for curie, *parts in reader
+            }
+
     # Set MIRA_NEO4J_URL in the environment
     # to point this somewhere specific
     client = Neo4jClient()
@@ -95,6 +116,7 @@ def startup_event():
         grounder=client.get_grounder(PREFIXES),
         refinement_closure=RefinementClosure(client.get_transitive_closure()),
         lexical_dump=client.get_lexical(),
+        vectors=vectors,
     )
 
     flask_app.register_blueprint(ui_blueprint)
diff --git a/setup.cfg b/setup.cfg
index 72b6bb17d..f5f60d9e1 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -75,6 +75,8 @@ web =
     python-libsbml
     lxml
     bioregistry
+    scipy
+    numpy
 uvicorn =
     uvicorn
 gunicorn =