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DESCRIPTION
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Package: placentaImmuneCellRefEPIC450k
Type: Package
Title: Placenta and Immune Cell Type DNA Methylation Microarray Deconvolution Reference
Version: 0.99.0
Authors@R:
c(
person("Kyle", "Campbell", email = "[email protected]", role = c("aut", "cre"),
comment=c(ORCID="
https://orcid.org/0000-0002-1836-0341")),
person("Kelly", "Bakulski", email = "[email protected]", role = c("ctb"),
comment=c(ORCID="
https://orcid.org/0000-0002-9605-6337")
)
)
Description: Companion package to "Placental and Immune Cell DNA
Methylation Reference Panel for Bulk Tissue Cell Composition Estimation in
Epidemiological Studies." This package provides the signature cell type matrix
of cell type-defining CpGs common to the 450k and EPIC microarrays for
5 placental (cytotrophoblast, endothelial, Hofbauer, stromal, and
syncytiotrophoblast), 6 peripheral immune (B cell, CD4T, CD8T, monocyte,
neutrophil, and natural killer), and nucleated red blood cell types. The
signature matrix is designed for plug and play use with EpiDISH's epidish(ref.m)
argument, Bioconductor R package, DOI <10.18129/B9.bioc.EpiDISH>. This data
package also includes the cell type samples' phenotype data used to create
the matrix. The fully processed complete beta value data matrix can be
accessed at accession number GSE271697 in the Gene Expression Omnibus hosted
at NCBI.
License: MIT
Encoding: UTF-8
LazyData: true
LazyDataCompression:gzip
Suggests:
knitr,
rmarkdown
VignetteBuilder: knitr
Depends: utils
biocViews: DNAMethylation, MethylationArray, Microarray, Software, TissueMicroarray