PermissionDenied:

[ralyodio]

error: Uncaught (in promise) PermissionDenied: Permission denied (os error 13)
    this.proc = Deno.run({
                     ^
    at Object.opSync (deno:core/01_core.js:172:12)
    at opRun (deno:runtime/js/40_process.js:28:17)
    at Object.run (deno:runtime/js/40_process.js:111:17)
    at BrowserRunner.start (https://deno.land/x/[email protected]/src/deno/BrowserRunner.ts:63:22)
    at ChromeLauncher.launch (https://deno.land/x/[email protected]/src/deno/Launcher.ts:108:12)

[jespertheend]

I had the same issue, removing the directory at $DENO_DIR/deno_puppeteer/chromium and reinstalling using install.ts fixed it for me.
(run deno info, to find out where your $DENO_DIR is)