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[BUG, MRG] Fix ACPC Coordinates in surface RAS when they should be in…
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… scanner RAS (#990)

* wip, helper functions don't work

* working version

* add PR number

* typo

* fix errors

* eric review
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alexrockhill authored Mar 31, 2022
1 parent 71130fc commit 3a60cb8
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Showing 9 changed files with 223 additions and 86 deletions.
2 changes: 2 additions & 0 deletions doc/api.rst
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Expand Up @@ -31,6 +31,8 @@ mne_bids
get_anat_landmarks
update_anat_landmarks
get_head_mri_trans
convert_montage_to_mri
convert_montage_to_ras
template_to_head
get_anonymization_daysback
search_folder_for_text
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2 changes: 1 addition & 1 deletion doc/whats_new.rst
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Expand Up @@ -57,7 +57,7 @@ Detailed list of changes
🪲 Bug fixes
^^^^^^^^^^^^

- ...
- Fix ACPC in ``surface RAS`` instead of ``scanner RAS`` in :ref:`ieeg-example` and add convenience functions :func:`mne_bids.convert_montage_to_ras` and :func:`mne_bids.convert_montage_to_mri` to help, by `Alex Rockhill`_ :gh:`990`

:doc:`Find out what was new in previous releases <whats_new_previous_releases>`

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15 changes: 11 additions & 4 deletions examples/convert_ieeg_to_bids.py
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Expand Up @@ -60,7 +60,8 @@
from mne_bids import (BIDSPath, write_raw_bids, write_anat,
get_anat_landmarks, read_raw_bids,
search_folder_for_text, print_dir_tree,
template_to_head)
template_to_head, convert_montage_to_ras,
convert_montage_to_mri)

# %%
# Step 1: Download the data
Expand Down Expand Up @@ -98,9 +99,10 @@
trans = mne.coreg.estimate_head_mri_t('sample_seeg', subjects_dir)

# %%
# Now let's convert the montage to "mri"
# Now let's convert the montage to "ras"
montage = raw.get_montage()
montage.apply_trans(trans) # head->mri
convert_montage_to_ras(montage, 'sample_seeg', subjects_dir) # mri->ras

# %%
# BIDS vs MNE-Python Coordinate Systems
Expand Down Expand Up @@ -237,13 +239,16 @@
raw2 = read_raw_bids(bids_path=bids_path)

# %%
# Now we have to go back to "head" coordinates with the head->mri transform.
# Now we have to go back to "head" coordinates.
#
# .. note:: If you were downloading this from ``OpenNeuro``, you would
# have to run the Freesurfer ``recon-all`` to get the transforms.

montage2 = raw2.get_montage()

# we need to go from scanner RAS back to surface RAS (requires recon-all)
convert_montage_to_mri(montage2, 'sample_seeg', subjects_dir=subjects_dir)

# this uses Freesurfer recon-all subject directory
montage2.add_estimated_fiducials('sample_seeg', subjects_dir=subjects_dir)

Expand All @@ -259,7 +264,9 @@
# the fiducials which are estimated; as long as the head->mri trans
# is computed with the same fiducials, the coordinates will be the same
# in ACPC space which is what matters
montage2 = raw.get_montage() # get montage in 'head' coordinates
montage = raw.get_montage() # the original montage in 'head' coordinates
montage.apply_trans(trans)
montage2 = raw2.get_montage() # the recovered montage in 'head' coordinates
montage2.apply_trans(trans2)

# compare with standard
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3 changes: 2 additions & 1 deletion mne_bids/__init__.py
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Expand Up @@ -14,4 +14,5 @@
get_anat_landmarks, anonymize_dataset)
from mne_bids.sidecar_updates import update_sidecar_json, update_anat_landmarks
from mne_bids.inspect import inspect_dataset
from mne_bids.dig import template_to_head
from mne_bids.dig import (template_to_head, convert_montage_to_ras,
convert_montage_to_mri)
2 changes: 1 addition & 1 deletion mne_bids/config.py
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Expand Up @@ -254,7 +254,7 @@
'ElektaNeuromag': 'head',
'ChietiItab': 'head',
'CapTrak': 'head',
'ACPC': 'mri', # assumes T1 is ACPC-aligned, if not the coordinates are lost # noqa
'ACPC': 'ras', # assumes T1 is ACPC-aligned, if not the coordinates are lost # noqa
'fsaverage': 'mni_tal', # XXX: note fsaverage and MNI305 are the same # noqa
'MNI305': 'mni_tal'
}
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91 changes: 89 additions & 2 deletions mne_bids/dig.py
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Expand Up @@ -4,6 +4,7 @@
# Alex Rockhill <[email protected]>
#
# License: BSD-3-Clause
import os.path as op
import json
from collections import OrderedDict
from pathlib import Path
Expand All @@ -14,7 +15,8 @@
import mne
import numpy as np
from mne.io.constants import FIFF
from mne.utils import logger, warn, _validate_type, _check_option
from mne.utils import (logger, warn, _validate_type, _check_option,
has_nibabel, get_subjects_dir)
from mne.io.pick import _picks_to_idx

from mne_bids.config import (ALLOWED_SPACES, BIDS_COORDINATE_UNITS,
Expand Down Expand Up @@ -416,7 +418,8 @@ def _write_dig_bids(bids_path, raw, montage=None, acpc_aligned=False,
"and left and right pre-auricular point "
"landmarks")

if bids_path.datatype == 'ieeg' and mne_coord_frame == 'mri':
if bids_path.datatype == 'ieeg' and bids_path.space in (None, 'ACPC') and \
mne_coord_frame == 'ras':
if not acpc_aligned:
raise RuntimeError(
'`acpc_aligned` is False, if your T1 is not aligned '
Expand Down Expand Up @@ -656,3 +659,87 @@ def template_to_head(info, space, coord_frame='auto', unit='auto',
info.set_montage(montage) # transform to head
# finally return montage
return info, mne.read_trans(data_dir / f'space-{space}_trans.fif')


@verbose
def convert_montage_to_ras(montage, subject, subjects_dir=None, verbose=None):
"""Convert a montage from surface RAS (m) to scanner RAS (m).
Parameters
----------
montage : mne.channels.DigMontage
The montage in the "mri" coordinate frame. Note: modified in place.
%(subject)s
%(subjects_dir)s
%(verbose)s
"""
if not has_nibabel(): # pragma: no cover
raise ImportError('This function requires nibabel.')
import nibabel as nib

subjects_dir = get_subjects_dir(subjects_dir, raise_error=True)
T1_fname = op.join(subjects_dir, subject, 'mri', 'T1.mgz')
if not op.isfile(T1_fname):
raise RuntimeError(f'Freesurfer subject ({subject}) and/or '
f'subjects_dir ({subjects_dir}, incorrectly '
'formatted, T1.mgz not found')
T1 = nib.load(T1_fname)

# transform from "mri" (Freesurfer surface RAS) to "ras" (scanner RAS)
mri_vox_t = np.linalg.inv(T1.header.get_vox2ras_tkr())
mri_vox_t[:3, :3] *= 1000 # scale from mm to m
mri_vox_trans = mne.transforms.Transform(
fro='mri', to='mri_voxel', trans=mri_vox_t)

vox_ras_t = T1.header.get_vox2ras()
vox_ras_t[:3] /= 1000 # scale from mm to m
vox_ras_trans = mne.transforms.Transform(
fro='mri_voxel', to='ras', trans=vox_ras_t)
montage.apply_trans( # mri->vox + vox->ras = mri->ras
mne.transforms.combine_transforms(mri_vox_trans, vox_ras_trans,
fro='mri', to='ras'))


@verbose
def convert_montage_to_mri(montage, subject, subjects_dir=None, verbose=None):
"""Convert a montage from scanner RAS (m) to surface RAS (m).
Parameters
----------
montage : mne.channels.DigMontage
The montage in the "ras" coordinate frame. Note: modified in place.
%(subject)s
%(subjects_dir)s
%(verbose)s
Returns
-------
ras_mri_t : mne.transforms.Transform
The transformation matrix from ``'ras'`` (``scanner RAS``) to
``'mri'`` (``surface RAS``).
"""
if not has_nibabel(): # pragma: no cover
raise ImportError('This function requires nibabel.')
import nibabel as nib

subjects_dir = get_subjects_dir(subjects_dir, raise_error=True)
T1_fname = op.join(subjects_dir, subject, 'mri', 'T1.mgz')
if not op.isfile(T1_fname):
raise RuntimeError(f'Freesurfer subject ({subject}) and/or '
f'subjects_dir ({subjects_dir}, incorrectly '
'formatted, T1.mgz not found')
T1 = nib.load(T1_fname)

# transform from "ras" (scanner RAS) to "mri" (Freesurfer surface RAS)
ras_vox_t = T1.header.get_ras2vox()
ras_vox_t[:3, :3] *= 1000 # scale from mm to m
ras_vox_trans = mne.transforms.Transform(
fro='ras', to='mri_voxel', trans=ras_vox_t)

vox_mri_t = T1.header.get_vox2ras_tkr()
vox_mri_t[:3] /= 1000 # scale from mm to m
vox_mri_trans = mne.transforms.Transform(
fro='mri_voxel', to='mri', trans=vox_mri_t)
montage.apply_trans( # ras->vox + vox->mri = ras->mri
mne.transforms.combine_transforms(ras_vox_trans, vox_mri_trans,
fro='ras', to='mri'))
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