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DESCRIPTION
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Package: TriadSim
Title: Simulating Triad Genomewide Genotypes
Version: 0.2.0
Authors@R: person("Min", "Shi", email = "[email protected]", role = c("aut", "cre"))
Description: Simulate genotypes for case-parent triads, case-control, and quantitative trait samples with realistic linkage diequilibrium structure and allele frequency distribution. For studies of epistasis one can simulate models that involve specific SNPs at specific sets of loci, which we will refer to as "pathways". TriadSim generates genotype data by resampling triad genotypes from existing data. The details of the method is described in the manuscript under preparation "Simulating Autosomal Genotypes with Realistic Linkage Disequilibrium and a Spiked in Genetic Effect" Shi, M., Umbach, D.M., Wise A.S., Weinberg, C.R.
Depends: R (>= 3.2.2)
License: GPL-3
biocViews: snpStats
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.1
Imports: methods, parallel, snpStats, foreach, doParallel, doRNG
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2020-07-12 03:18:13 UTC; shi2
Author: Min Shi [aut, cre]
Maintainer: Min Shi <[email protected]>
Repository: CRAN
Date/Publication: 2020-07-12 15:30:06 UTC