When NOT to use NATS?

[Codebreaker101]

Since the day I've discovered NATS I'm having trouble NOT using it everywhere. So far I've used it as a replacement for:

• Service-to-Service request-response invocation using HTTP, gRPC or rSocket with NATS Request-Reply
• Service discovery using Consul with NATS subjects
• Service request load balancing with NATS Queue groups
• Service mesh using Istio/Envoy with NATS micro
• Distributed configuration using Consul KV with NATS KV
• Event Log processing using Kafka with NATS JetStream

The only thing that NATS didn't replace are databases and service orchestrator (Nomad, in my case).

My question to you is - in what circumstances one should NOT to use NATS and what solution should be used instead?