diff --git a/redis/asyncio/connection.py b/redis/asyncio/connection.py
index 862f6f096b..e77fba30da 100644
--- a/redis/asyncio/connection.py
+++ b/redis/asyncio/connection.py
@@ -925,7 +925,8 @@ def pack_commands(self, commands: Iterable[Iterable[EncodableT]]) -> List[bytes]
                     or chunklen > buffer_cutoff
                     or isinstance(chunk, memoryview)
                 ):
-                    output.append(SYM_EMPTY.join(pieces))
+                    if pieces:
+                        output.append(SYM_EMPTY.join(pieces))
                     buffer_length = 0
                     pieces = []
 
diff --git a/redis/connection.py b/redis/connection.py
index b2f34293a5..24614824c5 100644
--- a/redis/connection.py
+++ b/redis/connection.py
@@ -976,7 +976,8 @@ def pack_commands(self, commands):
                     or chunklen > buffer_cutoff
                     or isinstance(chunk, memoryview)
                 ):
-                    output.append(SYM_EMPTY.join(pieces))
+                    if pieces:
+                        output.append(SYM_EMPTY.join(pieces))
                     buffer_length = 0
                     pieces = []