diff --git a/lib/bunny/exceptions.rb b/lib/bunny/exceptions.rb
index 0a202f91a..c00efc194 100644
--- a/lib/bunny/exceptions.rb
+++ b/lib/bunny/exceptions.rb
@@ -97,6 +97,12 @@ def initialize(frame)
     end
   end
 
+  class ConnectionAlreadyClosed < Exception
+    def initialize
+      super('Connection has been already closed')
+    end
+  end
+
   class ShutdownSignal < Exception
   end
 
diff --git a/lib/bunny/session.rb b/lib/bunny/session.rb
index e895fe455..f6e88cd10 100644
--- a/lib/bunny/session.rb
+++ b/lib/bunny/session.rb
@@ -325,6 +325,7 @@ def start
         @status_mutex.synchronize { @status = :not_connected }
         raise TCPConnectionFailedForAllHosts
       end
+      @status_mutex.synchronize { @manually_closed = false }
 
       self
     end
@@ -343,6 +344,7 @@ def transport_write_timeout
     # @return [Bunny::Channel] Newly opened channel
     def create_channel(n = nil, consumer_pool_size = 1, consumer_pool_abort_on_exception = false, consumer_pool_shutdown_timeout = 60)
       raise ArgumentError, "channel number 0 is reserved in the protocol and cannot be used" if 0 == n
+      raise ConnectionAlreadyClosed if manually_closed?
 
       @channel_mutex.synchronize do
         if n && (ch = @channels[n])
@@ -369,7 +371,10 @@ def close
 
         clean_up_on_shutdown
       end
-      @status_mutex.synchronize { @status = :closed }
+      @status_mutex.synchronize do
+        @status = :closed
+        @manually_closed = true
+      end
     end
     alias stop close
 
@@ -404,6 +409,11 @@ def closed?
       @status_mutex.synchronize { @status == :closed }
     end
 
+    # @return [Boolean] true if this AMQP 0.9.1 connection has been programmatically closed
+    def manually_closed?
+      @status_mutex.synchronize { @manually_closed == true }
+    end
+
     # @return [Boolean] true if this AMQP 0.9.1 connection is open
     def open?
       @status_mutex.synchronize do
diff --git a/spec/issues/issue465_spec.rb b/spec/issues/issue465_spec.rb
new file mode 100644
index 000000000..efbb83a72
--- /dev/null
+++ b/spec/issues/issue465_spec.rb
@@ -0,0 +1,32 @@
+# -*- coding: utf-8 -*-
+require 'spec_helper'
+
+describe Bunny::Session do
+  let(:connection) do
+    c = Bunny.new(
+        user: 'bunny_gem', password: 'bunny_password',
+        vhost: 'bunny_testbed',
+        port: ENV.fetch('RABBITMQ_PORT', 5672)
+    )
+    c.start
+    c
+  end
+
+  context 'after the connection has been manually closed' do
+    before :each do
+      connection.close
+    end
+
+    after :each do
+      connection.close if connection.open?
+    end
+
+    describe '#create_channel' do
+      it 'should raise an exception' do
+        expect {
+          connection.create_channel
+        }.to raise_error(Bunny::ConnectionAlreadyClosed)
+      end
+    end
+  end
+end