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DESCRIPTION
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Package: HyDDG
Title: Hypergeometric Distribution for Detecting DEGs
Version: 0.0.1
Authors@R:
c(person("Yun", "Zhu", email = "[email protected]",
role = c("aut", "cre")),
person("Yanzhe", "Xu", email = "[email protected]",
role = "aut"),
person("Juergen","Borlak",email = "[email protected]",
role = "aut"))
Description: HyDDG provides a suite of tools to detect differentially expressed genes
(DEGs) using a hypergeometric distribution-based approach. This package allows users
to compute fold changes, perform statistical tests for up- and down-regulated genes,
and adjust p-values for multiple testing. The core functionality includes calculating
statistical significance for each gene based on experimental and control group data,
and outputs meaningful DEGs with recommended thresholds for fold change and FDR.
It is specifically designed for transcriptomics data analysis, making it ideal for
researchers working in bioinformatics and computational biology.
License: GPL-3
Encoding: UTF-8
LazyData: true
Imports:
stats,
utils,
Biobase (>= 2.0)
Suggests:
BiocManager,
CLL
Depends:
R (>= 4.0.0)
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3