diff --git a/CHANGES.rst b/CHANGES.rst
index 4186a906..e2079cb6 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -5,6 +5,9 @@
 6.4 (unreleased)
 ================
 
+- Adjust for incompatible changes in Python 3.13b1.
+  (`#292 <https://github.com/zopefoundation/zope.interface/issues/292>`)
+
 - Build windows wheels on GHA.
 
 6.3 (2024-04-12)
diff --git a/src/zope/interface/_compat.py b/src/zope/interface/_compat.py
index 2ff8d83e..dd1cedb2 100644
--- a/src/zope/interface/_compat.py
+++ b/src/zope/interface/_compat.py
@@ -29,7 +29,10 @@ def _normalize_name(name):
         return name
     raise TypeError("name must be a string or ASCII-only bytes")
 
+
 PYPY = hasattr(sys, 'pypy_version_info')
+_version = sys.version_info
+IS_PY313_OR_GREATER = _version.major == 3 and _version.minor >= 13
 
 
 def _c_optimizations_required():
diff --git a/src/zope/interface/interface.py b/src/zope/interface/interface.py
index 733e3954..8e0d9ad2 100644
--- a/src/zope/interface/interface.py
+++ b/src/zope/interface/interface.py
@@ -802,6 +802,9 @@ def update_value(aname, aval):
                 # __static_attributes__: Python 3.13a6+
                 # https://github.com/python/cpython/pull/115913
                 '__static_attributes__',
+                # __firstlineno__: Python 3.13b1+
+                # https://github.com/python/cpython/pull/118475
+                '__firstlineno__',
             )
             and aval is not _decorator_non_return
         }
diff --git a/src/zope/interface/tests/test_advice.py b/src/zope/interface/tests/test_advice.py
index a5432011..cad36869 100644
--- a/src/zope/interface/tests/test_advice.py
+++ b/src/zope/interface/tests/test_advice.py
@@ -51,10 +51,22 @@ def test_w_class(self):
             self.assertTrue(d is advisory_testing.my_globals)
 
     def test_inside_function_call(self):
+        from zope.interface._compat import IS_PY313_OR_GREATER
         from zope.interface.advice import getFrameInfo
         kind, module, f_locals, f_globals = getFrameInfo(sys._getframe())
         self.assertEqual(kind, "function call")
-        self.assertTrue(f_locals is locals()) # ???
+
+        if IS_PY313_OR_GREATER:
+            # Python 3.13b1 implements PEP 667, which changes the type of
+            # ``f_locals`` from a mapping to a ``FrameLocalsProxy`` object
+            # while the return value of ``locals()`` is still a mapping, so
+            # they no longer point to the same object.
+            # See https://peps.python.org/pep-0667 and
+            # https://github.com/python/cpython/pull/115153
+            self.assertDictEqual(dict(f_locals), locals())
+        else:
+            self.assertTrue(f_locals is locals()) # ???
+
         for d in module.__dict__, f_globals:
             self.assertTrue(d is globals())