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Merge pull request #102 from AlexsLemonade/jaclyn-taroni/add-admin
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Add administrative document; move code and data availability to methods
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jaclyn-taroni authored Mar 25, 2024
2 parents ebbeac5 + 8027ca7 commit 397aa4e
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14 changes: 14 additions & 0 deletions content/04.methods.md
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Expand Up @@ -164,3 +164,17 @@ Multiplexed libraries were not converted to `AnnData` objects, due to the potent
All merged `SingleCellExperiment` objects were converted to `AnnData` objects and saved as `.hdf5` files.
If a merged `SingleCellExperiment` object contained any ADT data, the RNA and ADT data were exported and saved separately as RNA (`_rna.hdf5`) and ADT (`_adt.hdf5`) objects.
In contrast, if a merged `SingleCellExperiment` object contained HTO data due to the presence of any multiplexed libraries in the merged object, the HTO data was removed from the `SingleCellExperiment` object and not included in the exported `AnnData` object.

## Code and data availability

All summarized gene expression data and de-identified metadata are available for download on the ScPCA Portal, <https://scpca.alexslemonade.org/>.

Documentation for the Portal can be found at <https://scpca.readthedocs.io>.

All original code was developed within the following repositories and is publicly available as follows:

- The `scpca-nf` workflow used to process all samples available on the Portal can be found at <https://github.com/AlexsLemonade/scpca-nf>.
- The Single-cell Pediatric Cancer Atlas Portal code can be found at <https://github.com/AlexsLemonade/scpca-portal>.
- Benchmarking of tools used to build `scpca-nf` can be found at <https://github.com/AlexsLemonade/alsf-scpca/tree/main/analysis> and <https://github.com/AlexsLemonade/sc-data-integration/tree/main/celltype_annotation>.
- All code for the underlying figures can be found at <https://github.com/AlexsLemonade/scpca-paper-figures>.
- The manuscript can be found at <https://github.com/AlexsLemonade/ScPCA-manuscript>.
13 changes: 0 additions & 13 deletions content/05.code-and-data-availability.md

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15 changes: 15 additions & 0 deletions content/06.administrative.md
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## Acknowledgments

We thank the data generators and submitters of the Single-cell Pediatric Cancer Atlas.

This work was funded through the Alex's Lemonade Stand Foundation Childhood Cancer Data Lab and Childhood Cancer Data Lab Postdoctoral Fellowship (SMF).

## Author Contributions

|Author|Contributions|
|---|---|{% for author in manubot.authors %}
|{{author.name}}|{% if author.contributions is string %}{{author.contributions}}{% else %}{% for contribution in author.contributions %}{{ contribution }}{% if not loop.last %}, {% endif %}{% endfor %}{% endif %}|{% endfor %}

## Declarations of Interest

AGH, JAS, SJS, DSM, DVP, NI, AY, KGW, CJB, JO, and JNT are or were employees of Alex's Lemonade Stand Foundation, a sponsor of this research.

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