Skip to content

Commit

Permalink
Updated overview-pipes.rst #5 #11
Browse files Browse the repository at this point in the history
  • Loading branch information
GwennyGit committed Jul 10, 2024
1 parent 846ea35 commit 9d1da72
Showing 1 changed file with 12 additions and 12 deletions.
24 changes: 12 additions & 12 deletions docs/source/overview-pipes.rst
Original file line number Diff line number Diff line change
Expand Up @@ -10,23 +10,23 @@ More information about these differnt types of pipelines can be found below.

.. hint::

Which type of pipeline to use with out data is heavily dependant on your organism,
available information for it and the data you wish to use as input.
Which type of pipeline to use is heavily dependent on your organism, available information for your organism
and the data you wish to use as input.

CarveMe + ModelPolisher based (CMPB) pipeline
---------------------------------------------
CarveMe + ModelPolisher based (``CMPB``) pipeline
-------------------------------------------------

The CMPB pipeline is based on generating a draft model using CarveMe and subsequently extending and polishing
The ``CMPB`` pipeline is based on generating a draft model using `CarveMe <https://github.com/cdanielmachado/carveme>`__ and subsequently extending and polishing
the model using various tools.

This pipeline can be run on an annotated genome or an already generated CarveMe model and requires very little additional
information to be run on its base settings.
However additional information can be added from
e.g. KEGG or BioCyc to perform an automated gapfilling using `refineGEMs <https://github.com/draeger-lab/refinegems>`__ :footcite:p:`bauerle2023genome`.
However, additional information can be added from
e.g. KEGG or BioCyc to perform an automated gapfilling using `refineGEMs <https://github.com/draeger-lab/refinegems/tree/dev-2>`__ :footcite:p:`bauerle2023genome`.

.. note::

Currently, the ModelPolisher connections is still under construction, but the pipeline
Currently, the ModelPolisher connection is still under construction, but the pipeline
can already be run.

.. toctree::
Expand All @@ -43,10 +43,10 @@ High-quality template based (HQTB) pipeline
The HQTB pipeline curates a new model from an annotated genome based on a high-quality template model
(plus corresponding annotated genome) and additional database information.

This pipeline aims to profit from already performed (manual) curation of the already existing model,
This pipeline aims to profit from already performed (manual) curation of an already existing model,
to carry this knowledge into the new model. The closer the template is to the original, the more knowledge
can potential be carried over. Therefore, this pipeline is more useful, if the user already has a model of
a similar organism to the one the new model should be curated for.
can potentially be carried over. Therefore, this pipeline is more useful, if the user already has a model of
a similar organism compared to the one for which the new model should be curated for.

.. toctree::
:maxdepth: 2
Expand All @@ -59,7 +59,7 @@ a similar organism to the one the new model should be curated for.
More ideas for pipelines
------------------------

Below are some ideas for pipelines, which may be implemented in future update(s):
Below are some ideas for pipelines, to be implemented in future update(s):

.. toctree::
PGAB <pipeline_idea>

0 comments on commit 9d1da72

Please sign in to comment.