Skip to content

Commit

Permalink
Merge pull request #31 from moritzschaefer/patch-2
Browse files Browse the repository at this point in the history
Add link to preprint and GitHub repository for 'CellWhispererer' method
  • Loading branch information
szalata authored Oct 18, 2024
2 parents 96d2a6d + afce32f commit a2ba5ea
Showing 1 changed file with 1 addition and 1 deletion.
2 changes: 1 addition & 1 deletion README.md
Original file line number Diff line number Diff line change
Expand Up @@ -47,7 +47,7 @@ We welcome contributions to this repository. Please open a pull request or an is
| Model | Paper | Code | Omic Modalities | Pre-training Dataset | Input Embedding | Architecture | SSL Tasks | Supervised Tasks | Zero-shot Tasks |
|----------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-------------------------------------------------------------|------------------------------------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|----------------------------------------------------------------------------------------------------------------------------------|---------------------------------------------------------------------------------------------------------------------|---------------------------------------------------------------------|------------------------------------------------------------------------|----------------------------------------------------------------------------------------------------------|
| CELLama | 📝[Choi et al. 2024](https://www.biorxiv.org/content/10.1101/2024.05.08.593094v1.full#ref-16) | [🛠GitHub](https://github.com/portrai-io/CELLama) | scRNA-seq, Spatial transcriptomics | Natural Language [SBERT](https://fq.pkwyx.com/default/https/aclanthology.org/D19-1410.pdf) | Other: Ordering with embedding of the natural language representation, additional cell annotations are added in natural language | Siamese encoders ([SBERT](https://fq.pkwyx.com/default/https/aclanthology.org/D19-1410.pdf)) | Contrastive loss | Cell type annotation | Cell type annotation, niche cell type featuring |
| CellWhisperer | 📝[Schaefer et al. 2024](https://openreview.net/forum?id=yWiZaE4k3K) | Soon | Bulk/scRNA-seq | Transcriptome data paired with natural language annotations | Geneformer- and BioBERT-based embedding models (contrastively fine-tuned) | Multimodal contrastive training of embedding models (CLIP) and transcriptome instruction fine-tuning of LLM (LLaVA) | None | Transcriptome-aware question-answering | Reference-free cell property prediction (cell types & states, disease states, organ of cell origin, ...) |
| CellWhisperer | 📝[Schaefer et al. 2024](https://www.biorxiv.org/content/10.1101/2024.10.15.618501v1) | [🛠GitHub](https://github.com/epigen/cellwhisperer) | Bulk/scRNA-seq | Transcriptome data paired with natural language annotations | Geneformer- and BioBERT-based embedding models (contrastively fine-tuned) | Multimodal contrastive training of embedding models (CLIP) and transcriptome instruction fine-tuning of LLM (LLaVA) | None | Transcriptome-aware question-answering | Reference-free cell property prediction (cell types & states, disease states, organ of cell origin, ...) |
| scInterpreter | 📝[Li et al. 2024](https://arxiv.org/abs/2402.12405) | None | scRNA-seq | Natural Language [GPT-3.5](https://api.openai.com/) and [Llama-13b](https://arxiv.org/abs/2302.13971) | Other: Ordering with embedding of the natural language representation | Decoder, [GPT-3.5](https://api.openai.com/) and [Llama-13b](https://arxiv.org/abs/2302.13971) | NTP with CE loss and instruction finetuning (GPT-3.5 closed-source) | None | Cell type annotation (LLMs frozen, only small MLP trained) |
| ChatCell | 📝❌[Fang et al. 2024](https://arxiv.org/abs/2402.08303) | [🛠GitHub](https://github.com/zjunlp/ChatCell) | scRNA-seq | Natural Language [T5](https://huggingface.co/docs/transformers/en/model_doc/t5) and [natural language instructions](https://huggingface.co/datasets/zjunlp/ChatCell-Instructions) | Other: Ordering with embedding as natural language with additional terms | Encoder-Decoder, [T5](https://huggingface.co/docs/transformers/en/model_doc/t5) | NTP with CE loss | None (conditional sequence generation, prompting) | Simulation, cell type annotation, drug sensitivity prediction |
| MarkerGeneBERT | 📝[Cheng et al. 2023](https://www.biorxiv.org/content/10.1101/2024.01.30.578115v1) | None | scRNA-seq | Natural Language, [PubMed](https://pubmed.ncbi.nlm.nih.gov/) and [PubMed Central](https://www.ncbi.nlm.nih.gov/pmc/) | Other: Natural language preprocessed with [SciBERT](https://arxiv.org/abs/1903.10676) | Encoder | MLM | Named Entity Recognition (NER), cell-biomarker sentence classification | None |
Expand Down

0 comments on commit a2ba5ea

Please sign in to comment.